專利授權區國立清華大學國際產學營運總中心 Operations Center for Industry Collaboration

搜尋專利授權區

關鍵字

» 新增關鍵字

選單

專利授權區

專利授權區
專利名稱(中)	環胜肽及其製備方法
專利名稱(英)	Cyclic RGD peptide and method for preparing the same
專利家族	中華民國：I747138 大陸：7375003 美國：11,485,756
專利權人	國立清華大學 100%
發明人	陳建添,溫學賢
技術領域	生化醫藥

專利摘要(英)
A method for preparing a cyclopeptide and a cyclopeptide preparing by the method are disclosed. The method includes the following steps: (A) providing compounds represented by the following formulas (I-1) and (I-2): (I-1) (I-2), wherein, G, Ra, Rb, Rc, Rd, and Re are defined in the specification; (B) performing a reaction between the compounds of formulas (I-1) and (I-2) to obtain a compound represented by the following formula (I-3): (I-3); and (C) performing a cyclization reaction of the compound of formula (I-3) with a catalyst of formula (II) and deprotection to obtain a compound represented by the following formula (III): (III) M(O)mL1yL2z (II) wherein, G’, Q, M, L1, L2, m, y, and z are defined in the specification.

專利摘要(英)

A method for preparing a cyclopeptide and a cyclopeptide preparing by the method are disclosed. The method includes the following steps: (A) providing compounds represented by the following formulas (I-1) and (I-2): (I-1) (I-2), wherein, G, Ra, Rb, Rc, Rd, and Re are defined in the specification; (B) performing a reaction between the compounds of formulas (I-1) and (I-2) to obtain a compound represented by the following formula (I-3): (I-3); and (C) performing a cyclization reaction of the compound of formula (I-3) with a catalyst of formula (II) and deprotection to obtain a compound represented by the following formula (III): (III) M(O)mL1yL2z (II) wherein, G’, Q, M, L1, L2, m, y, and z are defined in the specification.

聯絡資訊
承辦人姓名	李佳玲
承辦人電話	03-5715131 #62300
承辦人Email	cl.lee@mx.nthu.edu.tw