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專利授權區
專利名稱(中)	2,5-呋喃二甲酸之製備方法
專利名稱(英)	TRANSFORMANT FOR PRODUCING 2,5-FURANDICARBOXYLIC ACID AND PREPARING METHOD FOR 2,5-FURANDICARBOXYLIC ACID
專利家族	中華民國：I735113 美國：11,578,346
專利權人	國立清華大學 62.44% ,長春人造樹脂廠股份有限公司 18.78% ,大連化學工業股份有限公司 7.04% ,長春石油化學股份有限公司 11.74%
發明人	胡育誠,范玉南,周俊彥
技術領域	生化醫藥

專利摘要(中)
本發明提供一種生產2,5-呋喃二甲酸之轉型株，包含：戀臭假單胞菌以及至少一外源基因，所述外源基因為HmfH基因或HMFO基因，且外源基因嵌入戀臭假單胞菌之染色體中。本發明另提供一種2,5-呋喃二甲酸之製備方法，包含：提供包含5-羥甲基糠醛的反應基質，和進行發酵步驟。所述發酵步驟係於反應基質中接種所述生產2,5-呋喃二甲酸之轉型株，並於一發酵溫度下培養一發酵時間，以獲得一發酵物質，其中所述發酵物質中包含2,5-呋喃二甲酸。

專利摘要(中)

本發明提供一種生產2,5-呋喃二甲酸之轉型株，包含：戀臭假單胞菌以及至少一外源基因，所述外源基因為HmfH基因或HMFO基因，且外源基因嵌入戀臭假單胞菌之染色體中。本發明另提供一種2,5-呋喃二甲酸之製備方法，包含：提供包含5-羥甲基糠醛的反應基質，和進行發酵步驟。所述發酵步驟係於反應基質中接種所述生產2,5-呋喃二甲酸之轉型株，並於一發酵溫度下培養一發酵時間，以獲得一發酵物質，其中所述發酵物質中包含2,5-呋喃二甲酸。

專利摘要(英)
The invention relates to a transformant for producing 2,5-furandicarboxylic acid and a preparing method for 2,5-furandicarboxylic acid. The transformant includes a Pseudomonas putida and at least one exogenous gene, wherein the exogenous gene is an HmfH gene or an HMFO gene, and the exogenous gene is integrated into the chromosome of the Pseudomonas putida. The preparing method includes providing a reaction substrate including 5-hydroxymethylfurfural, and performing a fermentation step. In the fermentation step, the transformant for producing 2,5-furandicarboxylic acid is inoculated into the reaction substrate, and is cultured at a fermentation temperature for a fermentation time to obtain a fermented substance, wherein the fermented substance includes 2,5-furandicarboxylic acid.

專利摘要(英)

The invention relates to a transformant for producing 2,5-furandicarboxylic acid and a preparing method for 2,5-furandicarboxylic acid. The transformant includes a Pseudomonas putida and at least one exogenous gene, wherein the exogenous gene is an HmfH gene or an HMFO gene, and the exogenous gene is integrated into the chromosome of the Pseudomonas putida. The preparing method includes providing a reaction substrate including 5-hydroxymethylfurfural, and performing a fermentation step. In the fermentation step, the transformant for producing 2,5-furandicarboxylic acid is inoculated into the reaction substrate, and is cultured at a fermentation temperature for a fermentation time to obtain a fermented substance, wherein the fermented substance includes 2,5-furandicarboxylic acid.

聯絡資訊
承辦人姓名	李馥如