專利授權區國立清華大學國際產學營運總中心 Operations Center for Industry Collaboration

搜尋專利授權區

關鍵字

» 新增關鍵字

選單

專利授權區

專利授權區
專利名稱(中)	用於偵測檢體中冠狀病毒的棘蛋白受體結合域與人類第二型血管收縮素轉換酶結合的方法及平台
專利名稱(英)	METHOD AND PLATFORM FOR ENHANCING DETECTION ACTIVITY OF INTERACTION BETWEEN SPIKE PROTEIN RECEPTOR BINDING DOMAIN OF CORONAVIRUS FROM SPECIMEN AND HUMAN ANGIOTENSIN-CONVERTING ENZYME II
專利家族	中華民國：I800853 美國：US 2022/0412959 A1(公開號)
專利權人	國立清華大學 100%
發明人	王慧菁
技術領域	生化醫藥

專利摘要(英)
The present disclosure provides a method and a platform for detecting binding ofa spike protein receptor binding domain of coronavirus in a specimen with a human angiotensin-converting enzyme II. The method and the platform of the presentdisclosure use a cleavable luciferase as a report test for the combination of a spike protein receptor binding domain of coronavirus (such as novel coronavirus) andangiotensin-converting enzyme II. Screening is carried out at the cellular level. The strength of the drug’s influence on the interaction between the two molecules can bejudged by the strength of the luminescence signal. The detection time can be completedwithin 20 minutes.

專利摘要(英)

The present disclosure provides a method and a platform for detecting binding ofa spike protein receptor binding domain of coronavirus in a specimen with a human angiotensin-converting enzyme II. The method and the platform of the presentdisclosure use a cleavable luciferase as a report test for the combination of a spike protein receptor binding domain of coronavirus (such as novel coronavirus) andangiotensin-converting enzyme II. Screening is carried out at the cellular level. The strength of the drug’s influence on the interaction between the two molecules can bejudged by the strength of the luminescence signal. The detection time can be completedwithin 20 minutes.

聯絡資訊
承辦人姓名	劉千綺
承辦人電話	03-571-5131 #31181
承辦人Email	chienchi@mx.nthu.edu.tw