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專利授權區


專利授權區
專利名稱(中) PHARMACEUTICAL COMPOSITION FOR ORAL DELIVERY OF HYDROPHOBIC SMALL MOLECULE DRUG AND HYDROPHILIC SMALL MOLECULE DRUG CONCURRENTLY
專利名稱(英) PHARMACEUTICAL COMPOSITION FOR ORAL DELIVERY OF HYDROPHOBIC SMALL MOLECULE DRUG AND HYDROPHILIC SMALL MOLECULE DRUG CONCURRENTLY
專利家族 美國:US-2020-0146973-A1(公開號)
專利權人 國立清華大學 100%
發明人 林柏諺,宋信文
技術領域 生化醫藥
專利摘要(中)
A pharmaceutical composition for oral delivery is provided with a poor ly water-soluble drug; solvent with lipophilic tails and hydrophi lic ends; an acid init iator; and a foaming agent generating c arbon dioxide bubbles when the acid i n i t i ator is dissolved into the intestinal f luid to form an acidic environment . The poor ly water-soluble drug is dissolved in the solvent to form a self-assembled monolayer car r ier system wi th the bile salts sur rounding the carbon dioxide bubbles in water when the pharma ceutic al compos i tion i s dis solved in an intes t inal tr ac t, and l ipid oi l drops containing the poorly water-soluble drug form when the carbon dioxide bubbles burst at the air-l iquid interface in the intes t inal tract.
聯絡資訊
承辦人姓名 蔡昀臻
承辦人電話 03-5715131 #31036
承辦人Email yunchen@mx.nthu.edu.tw
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