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專利授權區
專利名稱(中)	多病毒檢測裝置、系統及其使用方法
專利名稱(英)	MULTI-VIRUS DETECTION DEVICE, SYSTEM AND METHOD OF USING THE SAME
專利家族	中華民國：I852718 美國：US2025/0050339A1(公開號)
專利權人	國立清華大學 100.00%
發明人	李國賓,邱建欣,王志宏
技術領域	生化醫藥

專利摘要(中)
本發明揭示一種多病毒檢測裝置，並包含控制模組，以及微流道晶片。控制模組包括一組電磁鐵陣列。微流道晶片包括含有二個以上的流道單元的流道板、電磁板，以及至少二組磁珠件。每一流道單元含有數個孔洞，及數個閥門。該電磁板包含電磁感應件，及多個對應於該等孔洞且與其共同形成多個開放井的貫穿孔。每一磁珠件含有多個經適體修飾的磁珠且位於該等開放井。電磁鐵陣列可在電磁感應件的下方產生不同的磁場，將磁珠件固定於該等開放井。透過磁場控制電磁感應件開啟該等閥門，使該樣品可與磁珠件接觸，進而使磁珠上的適體抓取待測病毒。

專利摘要(中)

本發明揭示一種多病毒檢測裝置，並包含控制模組，以及微流道晶片。控制模組包括一組電磁鐵陣列。微流道晶片包括含有二個以上的流道單元的流道板、電磁板，以及至少二組磁珠件。每一流道單元含有數個孔洞，及數個閥門。該電磁板包含電磁感應件，及多個對應於該等孔洞且與其共同形成多個開放井的貫穿孔。每一磁珠件含有多個經適體修飾的磁珠且位於該等開放井。電磁鐵陣列可在電磁感應件的下方產生不同的磁場，將磁珠件固定於該等開放井。透過磁場控制電磁感應件開啟該等閥門，使該樣品可與磁珠件接觸，進而使磁珠上的適體抓取待測病毒。

專利摘要(英)
This invention discloses a multi-virus detection device comprises a control module, and a micro-channel chip. The control module includes an electro-magnet array. The micro-channel chip includes a flow channel plate containing at least two flow channel units, an electromagnetic board, and a least two sets of magnetic bead packages. Each flow channel unit contains several perforations, and several valves. The electromagnetic board contains an electromagnetic induction package, and several through-holes corresponding to the perforations. The through-holes and the perforations cooperate to confine several opened-wells. Each set of magnetic bead package contains several magnetic beads which are modified with aptamer and being in these opened-wells. The electro-magnet array can generate different magnetic fields in order to fix these magnetic bead packages in those opened-wells. Meanwhile, these micro-valves are opened by the electromagnetic induction packages through controlling the magnetic fields, and the sample and these magnetic bead packages are attracted each other to cause the aptamer of these magnetic bead to capture multiple virus to be measured.

專利摘要(英)

This invention discloses a multi-virus detection device comprises a control module, and a micro-channel chip. The control module includes an electro-magnet array. The micro-channel chip includes a flow channel plate containing at least two flow channel units, an electromagnetic board, and a least two sets of magnetic bead packages. Each flow channel unit contains several perforations, and several valves. The electromagnetic board contains an electromagnetic induction package, and several through-holes corresponding to the perforations. The through-holes and the perforations cooperate to confine several opened-wells. Each set of magnetic bead package contains several magnetic beads which are modified with aptamer and being in these opened-wells. The electro-magnet array can generate different magnetic fields in order to fix these magnetic bead packages in those opened-wells. Meanwhile, these micro-valves are opened by the electromagnetic induction packages through controlling the magnetic fields, and the sample and these magnetic bead packages are attracted each other to cause the aptamer of these magnetic bead to capture multiple virus to be measured.

聯絡資訊
承辦人姓名	劉千綺
承辦人電話	03-571-5131 #31181
承辦人Email	chienchi@mx.nthu.edu.tw