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專利授權區

專利授權區
專利名稱(中)	口服藥物組成物及其用途
專利名稱(英)	ORAL DRUG COMPOSITION AND USES THEREOF
專利家族	中華民國：I783175 美國：11,278,630
專利權人	國立清華大學 100%
發明人	宋信文,繆養寶,陳冠宏
技術領域	生化醫藥

專利摘要(英)
The invention relates to an oral drug composition including a prodrug and a carrier. The prodrug is formed by covalent bonding of an active drug to a spacer. The carrier includes β-1,3-D-glucan and is provided for carrying the prodrug with an efficient amount. Therefore, the oral drug composition can target microfold cells of the intestinal tract, allowing the oral drug composition of the present invention to effectively transport across the intestinal epithelium in a membrane phagocytic mode to break through the mucosal barrier to the desired location. Thus, the oral drug composition can be used to prepare anticancer drugs.

專利摘要(英)

The invention relates to an oral drug composition including a prodrug and a carrier. The prodrug is formed by covalent bonding of an active drug to a spacer. The carrier includes β-1,3-D-glucan and is provided for carrying the prodrug with an efficient amount. Therefore, the oral drug composition can target microfold cells of the intestinal tract, allowing the oral drug composition of the present invention to effectively transport across the intestinal epithelium in a membrane phagocytic mode to break through the mucosal barrier to the desired location. Thus, the oral drug composition can be used to prepare anticancer drugs.

聯絡資訊
承辦人姓名	李佳玲
承辦人電話	03-5715131 #62300
承辦人Email	cl.lee@mx.nthu.edu.tw