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專利授權區
專利名稱(中)	三維細胞培養與藥物測試篩選的陣列平台
專利名稱(英)	ARRAY PLATFORM FOR THREE-DIMENSIONAL CELL CULTURING AND DRUG TESTING AND SCREENING
專利家族	中華民國：I769861 大陸：CN 115478014 A(公開號) 美國：12,048,929
專利權人	臺北醫學大學 50.00% ,國立清華大學 50.00%
發明人	劉承賢,陳宥蓁,廖涵容,李岡遠,何淑娟,孫偉倫
技術領域	材料化工,生化醫藥,機械結構,電子電機

專利摘要(中)
本發明揭露一種三維細胞培養與藥物測試篩選的陣列平台。於此陣列平台中，水膠-細胞混合物注入區用以注入複數種水膠-細胞混合物。複數個細胞觀察區連接水膠-細胞混合物注入區。該些細胞觀察區之下方均設置有電極，並透過電極對該些細胞觀察區內的該複數種水膠-細胞混合物進行自動的細胞定量及三維細胞共排列，以仿造體內組織的結構。藥物注入區用以注入複數種藥物。複數個藥物組合產生器分別對應於該些細胞觀察區且均連接藥物注入區。該些藥物組合產生器均具有微流道結構且係用以根據該複數種藥物產生複數種藥物組合。

專利摘要(中)

本發明揭露一種三維細胞培養與藥物測試篩選的陣列平台。於此陣列平台中，水膠-細胞混合物注入區用以注入複數種水膠-細胞混合物。複數個細胞觀察區連接水膠-細胞混合物注入區。該些細胞觀察區之下方均設置有電極，並透過電極對該些細胞觀察區內的該複數種水膠-細胞混合物進行自動的細胞定量及三維細胞共排列，以仿造體內組織的結構。藥物注入區用以注入複數種藥物。複數個藥物組合產生器分別對應於該些細胞觀察區且均連接藥物注入區。該些藥物組合產生器均具有微流道結構且係用以根據該複數種藥物產生複數種藥物組合。

專利摘要(英)
An array platform for three-dimensional cell culturing and drug testing and screening is disclosed. In the array platform, a hydrogel-cell mixture injection area is used to inject kinds of hydrogel-cell mixtures. Cell observation areas are connected to the hydrogel-cell mixture injection area. Electrodes are disposed under the cell observation areas and automatic cell quantification and three-dimensional cell co-arrangement of the kinds of hydrogel-cell mixtures in the cell observation areas through the electrodes to imitate a structure of body’s tissues. A drug injection area is used to inject kinds of drugs. Drug combination generators respectively correspond to the cell observation areas and are connected to the drug injection area. The drug combination generators all have micro-flow channel structure and used to generate drug combinations according to the kinds of drugs.

專利摘要(英)

An array platform for three-dimensional cell culturing and drug testing and screening is disclosed. In the array platform, a hydrogel-cell mixture injection area is used to inject kinds of hydrogel-cell mixtures. Cell observation areas are connected to the hydrogel-cell mixture injection area. Electrodes are disposed under the cell observation areas and automatic cell quantification and three-dimensional cell co-arrangement of the kinds of hydrogel-cell mixtures in the cell observation areas through the electrodes to imitate a structure of body’s tissues. A drug injection area is used to inject kinds of drugs. Drug combination generators respectively correspond to the cell observation areas and are connected to the drug injection area. The drug combination generators all have micro-flow channel structure and used to generate drug combinations according to the kinds of drugs.

聯絡資訊
承辦人姓名	劉千綺
承辦人電話	03-571-5131 #31181
承辦人Email	chienchi@mx.nthu.edu.tw