專利授權區國立清華大學國際產學營運總中心 Operations Center for Industry Collaboration

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專利授權區

專利授權區
專利名稱(中)	用於精子分選、卵子培育以及體外受精的整合式晶片及方法
專利名稱(英)	INTEGRATED CHIP AND METHOD FOR SPERM SORTING, OOCYTE INCUBATION AND IN VITRO FERTILIZATION
專利家族	中華民國：I710630 大陸：CN 111073817 A(公開號) 美國：US 2020-0123484 A1(公開號)
專利權人	國立清華大學 100%
發明人	曾詠欽,陳約任,曾繁根
技術領域	生化醫藥

專利摘要(中)
An integrated chip is provided and comprises systems for sperm sorting, oocyte incubation and fertilization and liquid perfusion. The sperm sorting system comprises an inlet, an outlet, a main channel and a branch channel. The main channel has a width which increases along a direction from the inlet toward the outlet. The branch channel is connected to the main channel. The oocyte incubation and fertilization system is connected to the branch channel and comprises upper and lower holes. The upper hole is larger than the oocyte to hold the oocyte to be fertilized by a sperm. The lower hole is smaller than the oocyte. The sorted sperms are introduced into the oocyte incubation and fertilization system through the branch channel, to fertilize with the oocytes in the upper holes. The liquid perfusion system is located below the lower holes and a liquid exchange is performed through the second holes.

專利摘要(中)

An integrated chip is provided and comprises systems for sperm sorting, oocyte incubation and fertilization and liquid perfusion. The sperm sorting system comprises an inlet, an outlet, a main channel and a branch channel. The main channel has a width which increases along a direction from the inlet toward the outlet. The branch channel is connected to the main channel. The oocyte incubation and fertilization system is connected to the branch channel and comprises upper and lower holes. The upper hole is larger than the oocyte to hold the oocyte to be fertilized by a sperm. The lower hole is smaller than the oocyte. The sorted sperms are introduced into the oocyte incubation and fertilization system through the branch channel, to fertilize with the oocytes in the upper holes. The liquid perfusion system is located below the lower holes and a liquid exchange is performed through the second holes.

聯絡資訊
承辦人姓名	鍾弦靜