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專利授權區
專利名稱(中) 高壓縮性形狀記憶雙層網狀水膠及其使用與製備方法以及椎間盤支架
專利名稱(英) HIGHLY COMPRESSIBLE SHAPE MEMORY DOUBLE NETWORK HYDROGEL, USE AND PREPARATION METHOD THEREOF, AND INTERVERTEBRAL DISK SCAFFOLD
專利家族 中華民國:I802291
美國:US-2023-0263942-A1(公開號)
專利權人 國立清華大學 100.00%
發明人 王子威,何家宇
技術領域 材料化工,生化醫藥
專利摘要(中)
一種高壓縮性形狀記憶雙層網狀水膠,包括相互交織形成的第一網狀物和第二網狀物。所述第一網狀物是經化學性交聯的纖維素,且所述纖維素之間由醚基的形成完成所述化學性交聯。所述第二網狀物是經物理性交聯的褐藻酸,所述褐藻酸通過與二價金屬離子的反應完成所述物理性交聯。在所述高壓縮性形狀記憶雙層網狀水膠的製備過程中,先混合所述纖維素與所述褐藻酸,並在進行所述化學性交聯得到所述第一網狀物後,進行所述物理性交聯得到所述第二網狀物。
專利摘要(英)
A highly compressible shape memory double network hydrogel includes a first network and a second network interlaced each other. The first network is chemically cross-linked cellulose, and the chemical crosslinking is accomplished by the formation of ether groups between the celluloses. The second network is a physically cross-linked alginate, and the physical crosslinking is accomplished by reaction of the alginate with divalent metal ions. In the preparation process of the high compressible shape memory double network hydrogel, the cellulose and the alginate are mixed first, the chemical crosslinking is then performed to obtain the first network, followed by the physical crosslinking to obtain the second network.
聯絡資訊
承辦人姓名 楊美茹
承辦人電話 03-5715131 #62305
承辦人Email mjyang2@mx.nthu.edu.tw
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